Juvederm Lips Before And After

August 24, 2011

Silicone: Just the Facts Ma'am, Just the Facts

Filed under: Uncategorized — denisemiller0 @ 6:56 am

Silicone: Just the Facts Ma’am, Just the Facts
I am sure you are aware of the controversy in the past regarding silicone and breast implants and free silicone injections.  The explosion of the Internet and free web hosting now makes it possible for everyone in the world to have a website — or two or more! — of their own to display whatever it is they feel, believe in or would like to convey to the world.  Even if this means to misinform the universe, whether on purpose or not — it can be accomplished more easily through the Internet.  In this section we will discuss silica, silicon and silicone.  We will ultimately discuss how silicone is made and what its impacts on the body are.

Silica is silicon dioxide SiO2, it occurs in a crystalline state, an amorphous (shapeless) state and in impure forms such as quartz, opal and sand, respectively. “In the form of silicates it is present in most natural water supplies. Typical concentrations lie between 1 and 30 mg/L.  Higher concentrations may exist in brackish waters and brines. ” (3)

Silicon is a “nonmetallic element that occurs combined as the most abundant element next to oxygen in the earth’s crust and is used especially in alloys and electronic device” (Merriam-Webster).  It may not BE a metal but it is considered semi-metallic. In other words, “Silicon doesn’t occur in the free, elemental state, but is found in the form of silicon dioxide and complex silicates”.  It was discovered in 1824 by Jöns Jacob Berzelius. “Silicon is important in plant and animal life. Diatoms in both fresh and salt water extract silica from the water to use as a component of their cell walls”. (1) Silicon is used in many household items such as transistors, micro chips and electronics. Hence, Silicon Valley – the computer capital. 

Silicone is any of the “various polymeric organic silicon compounds obtained as oils, greases, or plastics and used especially for water-resistant and heat-resistant lubricants, varnishes, binders, and electric insulators” (Merriam-Webster)  It is also found in processed foods, cosmetics, medications and all sorts of products that you are exposed to and ingest on a daily basis.  It is also used to lubricate medical devices such as tubing, hypodermic needles and is found in the food industry as being used to lubricate blenders, frozen drink machines, piping, cooking utensils, and machines.

Silicones are synthetic polymers and are made by combining oxygen and silicon and in high temperatures and pressures can produce polydimethylsiloxane (PDMS).  The fluids are made from linear chains of PDMS whereas the gels are lightly crosslinked to give it a thicker cohesive-ness.  Although without a container such as a highly cross-linked silicone elastomer breast prosthesis the silicone gel takes on no shape of its own and is very vulnerable to gravity and momentum, if applicable.  The elastomer implant shells contain very little free PDMS so that it remains a solid.  However since like can not hold like for long, the lower-weighted molecular silicones bleed through the elastomer shells — even with the presence of “protective” inner barriers.

Silicone & Its Uses In the Body
Silicone products, in their solid form, have been used within the body for cosmetic applications for years and years without incident other than occasional sensitivity and encapsulation (which happens with all foreign bodies inserted into the human body as this is its way of sealing off the foreign object from the body).  Encapsulation is when the body forms a fibrous tissue capsule around a foreign body as it does not recognize it as its own — why would it? 

Solid silicone is used to augment or reconstruct the cheeks, the chin, the brow bone, calves, pectoral areas for men, as a replacement for lost digits, testicles and for buttock augmentation.  It is also used for joint replacements, rotary cuffs, and sockets — as well as a multitude of other medical uses.  

Liquid silicone is not approved for injection into the body for cosmetic applications but is approved for intra-ocular use for retinal tamponades.  Detached retinas can cause bleeding and blindness and silicone oil injections are used to help this.  It is, however, not approved to sculpt the lips, cheeks, buttocks, face, etc.  However since the oils (i.e. Silikon 1000 & Adatosil 5000) are approved in general, an amendment makes it so physicians are allowed to use approved drugs and devices off label as they see fit.

Unfortunately, silicone oil injections can cause granulomas, inflammatory nidus, macrophage activity and migration.  

gran*u*lo*ma (noun), plural -mas or -ma*ta
First appeared 1861
: a mass or nodule of chronically inflamed tissue with
granulations that is usu. associated with an infective process
— gran*u*lo*ma*tous (adjective)

mac*ro*phage (noun)
[International Scientific Vocabulary]
First appeared 1890
: a phagocytic tissue cell of the reticuloendothelial system that may
be fixed or freely motile, is derived from a monocyte, and functions
in the protection of the body against infection and noxious substances — called also histiocyte
— mac*ro*phag*ic (adjective)

…macrophages and other inflammatory responses (including chronic) is absolutely true when it comes to injected or free liquid silicone within the body.  Autoimmune disorders however have not been proven to be caused by silicone — either liquid or solid.

Regarding liquid silicone or (LIS), the infiltration of foreign substances of a certain molecular size/weight, can cause problems on a cellular level if they can not be successfully excreted or contained.  Many may argue that the goal should be not to inject or otherwise implant mobile substances of this size such as silicone oils and gels is something and that ideally it should be avoided.  

You may have heard Silicone referred to as inert.  Inert literally means static or immobile.  Although in the scientific world ‘inert’ is usually referring to chemically inert, or chemically non-reactive.  Silicone may be chemically inert, but it may not be biochemically inert. Biochemically inert would mean that these substances wouldn’t change composition in the body, but even the elastomer shell of breast implants degrade — they don’t last forever, nor would they cause reactions in the body.  It’s a fact, sorry.   

Inert, by definition, the material should not be able to migrate in a way that they may infiltrate a cellular structure, the surrounding subcutaneous tissue or an organ tissue, thereby smothering cells, and causing cell necrosis (death) nor would it inflame the surrounding tissues or cause sensitivity reactions. 

Personally, I don’t believe that silicone-based oils or gels or many synthetic substances can be classified as inert, by definition.  Reason being I have seen many cases of free silicone lip injection where the silicone has migrated to the chin region or even further down the neck, and has not stayed where it was supposed to — in the lip.  The fact is free silicone is known to migrate, therefore it is not completely inert, by definition, when injected into the lips, breasts, subcutaneous tissue, wherever. 

The FDA recognizes and warns of the fact of granulomatous, inflammatory responses, migration and discoloration of tissue after having had silicone injections — period.  Silicone injection is still being practiced on the black market and in plastic surgeons’ offices.  As liquid injectable silicone (LIS) was approved fo
r ophthalmic use only
.  Although some doctors are using LIS off-label for wrinkles, augmentation of lips, etc. advertising for such is illegal.  I even spoke to the FDA myself; I have the letter to prove it.  There is a loophole regarding the use of any product a physician deems suitable — as we will discuss further below — but the advertisement of off label use of any approved drug or device is illegal.  

Just remember that silicone can be problematic if in it’s migrating, liquid or gelatinous form if it enters a cell and suffocates it or you suffer from a chronic inflammatory response.  In fact, It is supposed to form granulomas so that it does not migrate — they rely on that granulomatous response to impede migration.

Auto Immune Disorders & Breast Implants or Silicone Implants
Siliconosis
This is an unofficial name that has been given to patients by other anti-breast implant activists who have 1 or more of 14 key disorders thought to be caused by silicone — including silicone injections, solid implants and breast implant shells and their silicone fillers, when applicable.

I know several people who had these disorders before they ever had any type of operation and the disorder never got any worse after breast augmentation or other types of surgeries involving silicone.   We routinely are exposed to silicone in our foods, eye drops. cosmetics, injections or any puncture by a hypodermic needle (which is lubricated by silicone).  Some may argue that yes, this is all true but we are not routinely exposed to such large amounts of silicone.  Well, yes you have a point.  And I never said that mass injections or intra tissue deposits of silicone were a good thing, did I? 

But we aren’t talking about cellular level problems and giant cell granulomas — we are talking about an immune response disease that are blamed for things such as:

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